茹嘉喜，博士，温州医科大学高等研究院副研究员/博士生导师；温医大第四层次（学术骨干）引进人才，2023年度入选“甬江人才”工程。至今在Inorg. Chem.、Anal. Chem.、ACS Appl. Mater. Interfaces、J. Mater. Chem. B、J. Hazard. Mater.等国际知名刊物上累计发表SCI论文49篇，其中一作（含共一）及通讯共计21篇。主持科研项目7项，包括国家自然科学基金青年基金1项和甘肃省自然科学基金项目1项。参编科学出版社专著1部。申请并授权国家发明专利12项。
工作经历
(1)2021.08 – 至今, 温州医科大学，高等研究院/慈溪生物医药研究院，副研究员
(2)2016.07 – 2021.08, 中国农业科学院兰州兽医研究所，低职高聘副研究员
课题组主要研究方向：
1、多模态成像指导下的精准治疗；
2、纳米药物递送载体及疫苗佐剂；
3、磷光化学传感器及时间分辨发光检测。
主持基金
中华人民共和国自然科学基金
国家自然科学基金青年科学基金项目，2020/01-2022/12，主持，已结题。
省级
甘肃省青年科技基金计划，2017/09-2019/09，主持，已结题。
中国农业科学院
中央级公益性科研院所基本科研业务费，院级统筹基本科研业务费， 2020/01-2021/12，已结题，主持
中央级公益性科研院所基本科研业务费，院级统筹基本科研业务费， 2018/01-2019/12，已结题，主持
中央级公益性科研院所基本科研业务费，所级统筹基本科研业务费， 2017/01-2017/12，已结题，主持
市级
宁波市自然科学基金一般项目，2023/06-2026/07，在研，主持
宁波市甬江人才工程，2023/06-2028/07，在研，主持
代表性论文(一作及通讯作者)
(1) Yu Chen, Chao Liang, Manchang Kou and Xiao-Liang Tang, Jiaxi Ru,* Lysosome-targeted Cyclometalated Ir(III) Complexes as Photosensitizer/Photoredox Catalysis for Cancer Therapy, Dalton Trans., 2024, 53(28), 11836–11849 (IF2023 = 3.5，SCI 二区）
(2) Jiaxi Ru,* Yu Chen, Siyi Tao, Shaobo Du, Chao Liang, Zhidong Teng,* and Yuan Gao*, Exploring Hollow Mesoporous Silica Nanoparticles as a Nanocarrier in the Delivery of Foot-And-Mouth Disease Virus-like Particle Vaccines. ACS Appl. Bio Mater., 2024, 7, 1064-1072. （IF2023 = 4.6）
(3) Peng Sun, Bingsheng Cheng, Jiaxi Ru, Xiaoyan Li, Guicun Fang, Yinli Xie, Guangjiang Shi, Jichao Hou, Longwei Zhao, Lipeng Gan, Lina Ma, Chao Liang, Yin Chen & Zhiyong Li. Nano-Carrier DMSN for Effective Multi-Antigen Vaccination Against SARS-CoV-2. Journal of Nanobiotechnology, 2024, 22(11), DOI: 10.1186/s12951-023-02271-w（IF2022 = 10.2，SCI 一区，top期刊，共同一作）
(4) Xiao Wang a, Xuechuan Wang a,c,*, Zhongxue Bai c, Jiaxi Ru b,**, Xiaoliang Zou c, Qingxin Han c,**. Fluorescent imaging and smartphone detection of ClO- using sensors based on trifluoromethylquinoline-substituted pyranonitrile. Sensors and Actuators B: Chemical, 2024, 402, 135120（IF2022 = 8.4，SCI 一区，top期刊）
(5) Hou, Fengping, Teng, Zhidong, Ru, Jiaxi, Liu, Haiyun; Li, Jiajun; Zhang, Yun; Sun, Shiqi*; Guo, Huichen*. Flower-like mesoporous silica nanoparticles as an antigen delivery platform to promote systemic immune response[J]. Nanomedicine: Nanotechnology, Biology, and Medicine, 2022, 42, （IF2020 = 6.458，共同一作）
(6) Jiaxi Ru, ‡a Weiyuan Xu,‡b Manchang Kou,c Hu Dong,d Xiaoliang Tang, *cYu Chen,a Lingling Kang,a Lixiong Dai*b and Chao Liang*. A novel Gd3+ DTPA-bisamide complex with high relaxivity as an MRI contrast agent[J]. J. Mater. Chem. B, 2023, 11, 7182 - 7189.（IF2021 = 7.571，SCI 二区）
(7) Xuerui Song, Chunlin Jing, Yingzhe Wang, Yan Feng, Chen Cao, Kun Wang, Weisheng Liu*, Jiaxi Ru*. Fluorescence distinguishing of SO2 derivatives and Cys/GSH from multi-channel signal patterns and visual sensing based on smartphone in living cells and environment[J]. Journal of Hazardous Materials, 2021, 413, 125332. （IF2021 = 14.2235, SCI 一区, Top 期刊）
(8) Jiaxi Ru, Xiaoliang Tang*, Zhenghua Ju, Guolin Zhang, Wei Dou, Xiangquan Mi, Chunming Wang and Weisheng Liu*. Exploitation and application of a highly sensitive Ru(II) complex-based phosphorescent chemodosimeter for Hg2+ in aqueous solutions and living cells[J]. ACS Appl. Mater. Interfaces. 2015, 7(7): 4247-56. （IF2021 = 10.3831, SCI 一区,, Top 期刊）
(9) Jiaxi Ru, Xu Chen, Liping Guan, Xiaoliang Tang*, Chunming Wang, Yue Meng, Guolin Zhang and Weisheng Liu*. Ratiometric iridium(III) complex-based phosphorescent chemodosimeter for Hg2+ applicable in time-resolved luminescence assay and live cell imaging[J]. Anal. Chem. 2015, 87(6): 3255-62. （IF2021 = 8.0084, SCI 一区, Top 期刊）
(10) Jia-Xi Ru, Li-Ping Guan, Xiao-Liang Tang*, Wei Dou, Xiang Yao, Wan-Min Chen, Ya-Ming Liu, Guo-Lin Zhang*, Wei-Sheng Liu*, Yue Meng and Chun-Ming Wang. Turn-on phosphorescent chemodosimeter for Hg2+ based on a cyclometalated Ir(III) complex and its application in time-resolved luminescence assays and live cell imaging[J]. Inorg. Chem. 2014, 53(21): 11498-506. （IF2021 = 5.436, SCI 二区, Top 期刊）
(11) Cao, Chen; Jing, Chunlin; Feng, Yan; Song, Xuerui; Liu, Weisheng; Zhang, Guolin*; Dou, Wei*; Ru, Jiaxi*. A novel bis-reaction-triggered cascade fluorescent probe for improved specific detection and biological visualization of Cys over Hcy/GSH. [J]. Dyes and Pigments, 2022, 197, 109823 （IF2020 = 4.888, SCI 一区, Top 期刊）
(12) Qingxin Han*, Lingna Yang, Yunyun Song, Jiaxi Ru*, Huijie Zhang, Huie Jiang, Xuechuan Wang*. A Ratiometric Fluorescent Probe for Monitoring the Changes in the Level of Hydrogen Polysulfides in Mitochondria During Stimulus-Induced Redox Imbalance[J]. Dyes and Pigments, 2021, 188, 109190. （IF2021 = 5.1222, SCI 一区, Top 期刊）
(13) Qingxin Han, Xuan Liu, Xuechuan Wang∗, Ruojun Yin, Huie Jiang, Jiaxi Ru∗∗, Weisheng Liu∗∗∗. Rational design of a lysosomal-targeted ratiometric two-photon fluorescent probe for imaging hydrogen polysulfides in live cells[J]. Dyes and Pigments, 2020, 173,107877 （IF2021 = 5.1222, SCI 一区, Top 期刊）
(14) Jiaxi Ru, Xiangquan Mi, Liping Guan, Xiaoliang Tang,* Zhenghua Ju, Guolin Zhang, Chunming Wang* and Weisheng Liu*. Design and application of a water-soluble phosphorescent Ru(II) complex as turn-on sensing material for Hg2+[J]. J. Mater. Chem. B, 2015, 3(30): 6205-12.（IF2021 = 7.571，SCI 二区）
(15) Zhijun Liu,‡ Jiaxi Ru,‡ Shiqi Sun, Zhidong Teng, Hu Dong, Pin Song, Yunshang Yang* and Huichen Guo*. Uniform dendrimer-like mesoporous silica nanoparticles as a nano-adjuvant for foot-and-mouth disease virus-like particle vaccine[J]. J. Mater. Chem. B, 2019, 7, 3446-3454（IF2021 = 7.571，SCI 二区）
(16) Hang Zhang,‡ Jiaxi Ru,‡ Xiaoliang Tang,* and Huichen Guo* Urchin-Like Porous Silica Nanoparticles for Simultaneous Intracellular Delivery of Doxorubicin and RNase A[J]. ACS Appl. Nano Mater. 2020, 3, 9993-10002 （IF2021 = 6.140，SCI 二区）
(17) Qingxin Han, Jiaxi Ru*, Xuechuan Wang*, Zhe Dong, Li Wang, Huie Jiang, and Weisheng Liu*. Photostable Ratiometric Two-Photon Fluorescent Probe for Visualizing Hydrogen Polysulfide in Mitochondria and Its Application[J]. ACS Appl. Bio Mater., 2019, 2, 5, 1987-1997
(18) Lan Wang, Zhi-Li Wei, Chang Liu, Wen-Kui Dong*, Jia-Xi Ru*. Synthesis and characterization for a highly selective bis(salamo)-based chemical sensor and imaging in living cells[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 239, 118496 （IF2021 = 4.831）
(19) Ruo-Yu Li, Zhi-Li Wei, Lan Wang, Yang Zhang*, Jia-Xi Ru*. A new salamo-based fluorescence probe to visually detect aluminum(III) ion and bio-imaging in zebrafish[J]. Microchemical Journal, 2021, 162, 105720（IF2021 = 5.304）
(20) Lu-Mei Pu*, Lan Wang, Zhi-Li Wei, Zhuang-Zhuang Chen, Hai-Tao Long, Jia-Xi Ru*, Xiu-Yan Dong*. A newly synthesized visual bis(salamo)-based fluorescent chemosensor for exogenous detection of B4O72− in living cells and zebrafish[J]. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2021, 249, 119263（IF2021 = 4.831）
(21) Yunqi Yang, Zhidong Teng, Yuanlu Lu, Xin Luo, Suyu Mu, Jiaxi Ru*, Xiang Zhao*, Huichen Guo, Xuhua Ran, Xiaobo Wen*, Shiqi Sun*. Enhanced immunogenicity of foot and mouth disease DNA vaccine delivered by PLGA nanoparticles combined with cytokine adjuvants[J]. Research in Veterinary Science, 2021, 136, 89-96. （IF2021 = 2.554）