聚焦各种急慢性因素，如糖尿病、肥胖和药物等导致组织损伤的分子机制；并探究成纤维细胞生长因子在其中的作用特征。以第一作者/最后通讯作者在Signal Transduction and Targeted Therapy，Cell Death & Disease等期刊发表论文多篇。主持国家自然科学基金面上项目、青年项目等多项。
入选浙江省“万人计划”青年拔尖人才。
1. 专业研究方向：FGFs在急慢性肾损伤和衰老中的作用特征
2. 科研项目：
1） 国家自然科学基金，面上项目，在研，主持
2） 宁波市自然科学基金，一般项目，在研，主持
3） 国家自然科学基金，青年项目，已结题，主持
4） 浙江省自然科学基金，一般项目，已结题，主持
3. 发表论文
[1] Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway. Minling Pan*, Zhen Wang*, Yiyi Wang*, Xianqin Jiang, Yali Fan, Fanghua Gong#, Yunpeng Sun#, Dezhong Wang#. Biomedicine & Pharmacotherapy. 2023 Oct:166:115333.
[2] FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression. Dezhong Wang*, Yuan Yin*, Shuyi Wang*, Tianyang Zhao*, Fanghua Gong, Yushuo Zhao, Beibei Wang, Yuli Huang, Zizhao Cheng, Guanghui Zhu, Zengshou Wang, Yang Wang, Jun Ren, Guang Liang#, Xiaokun Li#, Zhifeng Huang#. Signal Transduction and Targeted Therapy. 2021 Mar 24;6(1):133.
[3] PPARγ Mediates the Anti-Epithelial-Mesenchymal Transition Effects of FGF1ΔHBS in Chronic Kidney Diseases via Inhibition of TGF-β1/SMAD3 Signaling. Dezhong Wang*, Tianyang Zhao*, Yushuo Zhao*, Yuan Yin, Yuli Huang, Zizhao Cheng, Beibei Wang, Sidan Liu, Minling Pan, Difei Sun#, Zengshou Wang#, Guanghui Zhu#. Frontiers in Pharmacology. 2021 Jun 3;12:690535.
[4] FGF1ΔHBS ameliorates chronic kidney disease via PI3K/AKT mediated suppression of oxidative stress and inflammation. Dezhong Wang*, Mengyun Jin*, Xinyu Zhao*, Tianyang Zhao, Wei Lin, Zhengle He, Miaojuan Fan, Wei Jin, Jie Zhou, Lingwei Jin, Chao Zheng, Hui Jin, Yushuo Zhao, Xiaokun Li, Lei Ying, Yang Wang#, Guanghui Zhu#, Zhifeng Huang#. Cell Death & Disease. 2019 Jun 12;10(6):464.
E-mail：ran-air@163.com
通讯地址：温州医科大学生物医药科研大楼南楼10楼