聚焦于智能药物系统的开发与应用，特别是围绕细胞生长因子FGF等复合药物系统的创新设计与优化，致力于推动消化道疾病（如炎症性肠病、黏膜炎等）治疗的发展。此外，结合免疫细胞（如巨噬细胞）构建嵌合体系统，实现细胞生长因子FGF在炎症性部位的精准靶向调控。通过这些策略，致力于突破个体差异性、免疫炎性微环境等瓶颈，为个体化医疗提供新的理论依据和技术支持。以通讯或第一（含共同）作者在Biomaterials, ACS Nano, Journal of Nanobiotechnology等高质量SCI期刊发表研究论文20余篇；主持国家自然科学基金委青年项目等省部级项目。
入选温州市“瓯越英才”领军培养类人才项目和龙湾区青年创新拔尖人才。
1. 专业研究方向：智能药物系统的开发与应用
2. 科研项目：
1）国家自然科学基金，青年项目， 2022-01至2024-12，结题，主持
2）浙江省自然科学基金，国际合作项目， 2021-07至2024-12，结题，主持
3）科技部国家重点研发计划子项目，2022YFB3806400，未结题，主持
4）广东省自然科学基金，面上项目2019-01至2022-09，结题，主持
3. 发表论文
(#Co-first authors, *Corresponding author)
1. Hongyi jiang, Xinyi Zhu, jiachen Yu, Weidan Wang, Yiwen Mao, Liting Jiang, Liang Zhu, Hanting Shen, Chao Lou, Chihao Lin, Zhongnan Lin, Zijian Yan, Yumeng Wang, Jilong Wang*, Xinghe Xue*, Xiaoyun Pan*, Biomimetic extracellular vesicles based on composite bioactive ions for the treatment of ischemic bone disease. ACS Nano DOI: 10.1021/acsnano.4c13028（IF=15.8,一区TOP）
2. Jilong Wang, Chenghu Wu, Yiran Wang, Yecheng Shen, Kerui Wu, Yikai Shi, Tianshou Cao, Shanshan Yuan, Yuting Zhu, Yongheng Bai, Jinhai Huang*, Yan Zhang*, Junjie Deng*, Nano-enabled regulation of DNA damage in tumor cells to enhance neoantigen-based pancreatic cancer immunotherapy. Biomaterials 311 (2024) 122710 （IF=12.8, 医学一区TOP）
3. Hongyi Jiang, Weijie Xia, Tian Xia, Liting Jiang, Jiachen Yu, Xinyi Zhu, Chihao Lin, Chao Lou, Weidan Wang, Yingqian Chai, Renwen Wan, Jilong Wang∗, Xinghe Xue∗, Xiaoyun Pan∗, Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal−organic framework nanoparticles for ischemic osteonecrosis treatment. Acta Biomaterialia 185 (2024) 410–428（IF=9.4, 医学一区TOP）
4. Jiachen Yu, Hongyi Jiang, Hanting Shen, Liang Zhu, Xinghe Xue, Jian Lin*, Jilong Wang*, Xiaoyun Pan*, Unraveling the potential of nanozymes in the tapestry of orthopedic healing, Materials & Design 242 (2024) 113016（IF=7.6, 二区TOP）
5. Tian Xia, Yuting Zhu, Kaiqiang Li, Ke Hao, Yingqian Chai, Hongyi Jiang, Chao Lou, Jiachen Yu, Wei Yang, Jilong Wang*, Junjie Deng* and Zhen Wang*, Microneedles loaded with ceriummanganese oxide nanoparticles for targeting macrophages in the treatment of rheumatoid arthritis, Journal of Nanobiotechnology (2024) 22:103（IF=10.6, 一区TOP, 高被引）
6. Yingli Luo, Xianyu Luo, Yi Ru, Xinru Zhou, Didi Liu, Qian Huang, Maoyuan Linghu, Yuhang Wu, Zicheng Lv, Meimei Chen, Yinchu Ma*, Yi Huang*, and Jilong Wang*，Copper(II)-Based Nano-Regulator Correlates Cuproptosis Burst and Sequential Immunogenic Cell Death for Synergistic Cancer Immunotherapy, Biomaterials Research 2024;28: 0039（IF=8.1, 医学一区）
7. Zhuo Yan, Zhengbo Zhang, Yanan Chen, Jianghua Xu, Jilong Wang* and Zhangquan Wang*, Enhancing cancer therapy: the integration of oncolytic virus therapy with diverse treatments, Cancer Cell International (2024) 24:242（IF=5.3, 医学二区）
8. Chenghu Wu, Ning Lu, Lina Peng Minghao Lin, Yongheng Bai, Mingqin Lu*, Junjie Deng*, Jilong Wang* Regulation of inflammatory macrophages by oral mineralized metal-organic framework nanoparticles for the synergistic treatment of ulcerative colitis and liver injury, Chemical Engineering Journal, 468 (2023) 143655（IF=13.3, 一区TOP）
9. Chenghu Wu, Wenjuan He, Yue Chen, Jie Cai, Fanjun Zeng,* Zidong Lu,* Jilong Wang*, Personalized Bacteria Loaded with Autoantigens for the Enhancement of Tumor Immunotherapy, Advanced Healthcare Materials 2023, 2203026 （IF=10, 医学二区TOP）
10. Yinchu Ma, Yingli Luo, Xinfeng Tang, Wei Jiang, Hongjun Li, and Jilong Wang*. Ferric iron coordinated cisplatin prodrug reprograms the immune-cold tumor microenvironment through tumor hypoxia relief for enhanced cancer photodynamic-immunotherapy. Nano Research 16, 9930–9939 (2023). （IF=9.2, 二区）
11. Chao Lou, Hongyi Jiang, Zhongnan Lin, Tian Xia, Weidan Wang, Chihao Lin, Zhiguang Zhang, Haonan Fu, Shoaib Iqbal, Haixiao Liu, Jian Lin, Jilong Wang*, Xiaoyun Pan* and Xinghe Xue*, MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6, Journal of Nanobiotechnology (2023) 21:486 （IF=10.6, 一区TOP）
12. Hongyi Jiang, Chao Lou, Liting Jiang, Chihao Lin, Weidan Wang, Zijian Yan, Jiachen Yu, Tingwen Cai, Shida Lin, Jilong Wang*, Xiaoyun Pan*, Xinghe Xue*,Simvastatin-enhanced bioinspired exosome mimetics regulate osteogenesis and angiogenesis for the treatment of glucocorticoid-induced osteonecrosis of the femoral head, Chemical Engineering Journal 472 (2023) 144729（IF=13.3, 一区TOP）
E-mail：wangjilong@wmu.edu.cn
通讯地址：温州医科大学生物医药科研大楼南楼6楼